Clinical Opinion – Poll of the week

Poll of week 6

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Poll of the Week 6

Micafungin, caspofungin and anidulafungin are not active at clinically relevant concentrations against all of these except ?

Micafungin, caspofungin and anidulafungin are not active at clinically relevant concentrations against Zygomycetes, Cryptococcus neoformans, Fusarium spp., or Trichosporon spp.

Echinocandins show fungicidal activity against both C. albicans and a large group of non-albicans species, including species such as C. glabrata and C. krusei, which are intrinsically resistance to triazoles, and C. lusitaniae resistance to amphotericin B.

In cases of Aspergilli, echinocandins have fungistatic activity and reduce invasion via damage of hyphae and branching.

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