Up to 80% of patients with newly diagnosed multiple myeloma present with osteolytic lesions and bone disease. These patients are at high risk of skeletal related events, including pathological fractures, spinal cord compression, and need for surgical or radiotherapy. Skeletal-related events
substantially add to multiple myeloma’s disease burden and patient symptoms. This review focuses on imaging techniques and management of myeloma.
References:- IMWG guidelines
 Lancet Oncol 2021; 22: e119–30
- Treatment of multiple myeloma-related bone disease: recommendations from the Bone Working Group of the International Myeloma Working Group
 Lancet Oncol 2019; 20: e302–12
- International myeloma working group consensus recommendations on imaging in monoclonal plasma cell disorders